Holland America 2025-26 South America & Antarctica Cruises Now Booking

Holland America Line has opened bookings for its 2025-26 South America and Antarctica cruises, featuring visits to sixteen UNESCO World Heritage Sites and Biosphere Reserves. The Oosterdam will navigate routes between San Antonio (Santiago), Chile, and Buenos Aires, Argentina, or Fort Lauderdale, Florida, from November 2025 to March 2026.

The itineraries, ranging from 14 to 31 days, showcase iconic destinations like Iguazu Falls, Machu Picchu, Torres del Paine National Park, and Antarctica. A 31-day back-to-back cruise option combines the “Panama Canal and Inca Discovery” with the “South America Passage” itinerary. Travelers can explore cultural, historical, and ecological landmarks across the region, making for a vibrant and varied cruise experience. Dan Rough, Vice President of Revenue Management at Holland America Line, emphasizes the unique appeal of the mid-sized ships and curated itineraries that connect guests deeply to each destination.